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Immunopharmacology and Immunotoxicology

  • John W. Hadden
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 288)

Abstract

The two fields of immunopharmacology and immunotoxicology took their origins separately. Both derived from shared interests between areas of immunology and pharmacology. In the case of immunopharmacology the historical pressures which gave rise to its development lay in the need for a science of immunotherapy. In the case of immunotoxicology the pressures came from the need to extend toxicologic understandings to the recently elucidated systems of immunity. Once the fields began to congeal it was quickly recognized that the scientific processes involved represented two side of the same coin... i.e., “up regulation” and :“down regulation”. It was clear that the bases of the scientific methods of study were closely related -e.g., define the cellular targets, explore mechanisms of action, and integrate the in vivo effects to clarify the overall immunologic consequences to the organism in terms of resistance to cancer, infection, and autoimmunity.

Keywords

Transfer Factor Thymic Epithelial Cell Thymic Involution Sodium Diethyldithiocarbamate Thymic Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • John W. Hadden
    • 1
  1. 1.Division of ImmunopharmacologyUniversity of South Florida College of MedicineTampaUSA

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