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Partitioning of Plasmids in Streptomyces: Segregation in Continuous Culture of a Vector with Temperature-Sensitive Replication

  • M. Roth
  • G. Müller
  • M. Neigenfind
  • C. Hoffmeier
  • R. Geuther
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 55)

Abstract

Streptomycetes are not only important producers of nu­merous antibiotics and enzymes, but they are also of increa­sing interest as alternative bacterial hosts for the produc­tion of eukaryotic and other heterologous gene products. Recombinant vector plasmids with sufficient structural and segregational stability under non-selective conditions are necessary for this purpose.

Keywords

Continuous Culture Chemostat Culture Plasmid Copy Restrictive Temperature Hyphal Length 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • M. Roth
    • 1
  • G. Müller
    • 1
  • M. Neigenfind
    • 1
  • C. Hoffmeier
    • 1
  • R. Geuther
    • 1
  1. 1.Central Institute of Microbiology and Experimental TherapyAcademy of Sciences of the GDRJenaGermany

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