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Antibiotic Biosynthesis

  • Iain S. Hunter
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 55)

Abstract

Our knowledge and understanding of antibiotic biosynthesis has advanced significantly in recent years. The initial cloning of resistance genes in the early 1980’s (e.g. 1,2) was followed by the cloning of complete pathways (e.g. 3,4). Without exception, antibiotic production genes in streptomycetes are clustered on the chromosome. Often a resistance genes (or genes) is also located within the cluster (e.g. 5,6) which provides a facile strategy for cloning the others. Many different strategies nave been used for cloning production genes (reviewed 7).

Keywords

Biosynthetic Gene Antibiotic Production Antibiotic Biosynthesis Complete Pathway EMBO Journal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Iain S. Hunter
    • 1
  1. 1.Institute of GeneticsUniversity of GlasgowGlasgowUK

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