Advertisement

The Effect of Intermittent Scrotal Hyperthermia on the Sprague-Dawley Rat Testicle

  • Kevin R. Loughlin
  • Kelledy Manson
  • Russell Foreman
  • Beth Schwartz
  • Phyllis Heuttner
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 286)

Abstract

Twenty-four mature male Sprague-Dawley rats were divided into 2 groups of 12. One group was exposed to intermittent hot baths for 1 month, while the other group was exposed to room temperature baths. The group that was exposed to the elevated temperature demonstrated histological testicular changes that included decreased tubular diameter, basement membrane thinning, and decreased spermatogenesis. Fertility rates were markedly reduced in the heat exposed group, but complete recovery of fertility occurred by 10 weeks after completion of the heat treatments.

Keywords

Leydig Cell Fertility Impairment Tubular Diameter Testicular Blood Flow Hyperthermia Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Saypol, D.C., Howards, S.S., Turner, T.T., and Miller, E.D. Jr.: Influence of surgically induced varicocele on testicular blood flow, temperature and histology in adult rats and dogs.J. Clin. Invest. 68:39 (19821CrossRefGoogle Scholar
  2. 2.
    Saypol, D.C.: Varicocele.J. Androl. 2:61 (1981).Google Scholar
  3. 3.
    Hoffer, A.P., Agarwal, A., Meltzer, P., Nagvi, R., and Matlin, S.A.: Antifertility, spermicidal and ultrastructural effects of gossypol and derivatives administered orally by intratesticular injections.Contraception37:301 (1988).PubMedCrossRefGoogle Scholar
  4. 4.
    Zorgniotti, A.W. and MacLeod, J.: Studies in temperature, human semen quality and varicocele.Fertil. Steril. 24:854 (1973).PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Kevin R. Loughlin
    • 1
  • Kelledy Manson
    • 1
  • Russell Foreman
    • 1
  • Beth Schwartz
    • 1
  • Phyllis Heuttner
    • 1
  1. 1.Division of Urology Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA

Personalised recommendations