Factors of the Pathogenicity of Candida Albicans — A Review

  • L. Krempl-Lamprecht
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 50)


Candida albicans, the most common cause of pathological yeast infections, is an opportunistic fungus. That means it has specific attributes of pathogenicity, but these different factors can produce a mycosis only if the host is predisposed and reduced in his antimicrobial defense. Therefore, great differences are seen in the severity of a Candida-mycosis. They are caused by the fungus as well as by the host:
  1. 1)

    Different strains of the yeast possess different degrees of virulence. So a low or a high propensity to cause diseases may be observed.

  2. 2)

    The resistance of the host is varying, too: If there is a limited failure of the defense mechanisms, Candida invades superficially. If the defects are serious and numerous, a deep seated mycosis may arise. In patients with T-cell dysfunction ainly chronical infections occur.



Candida Albicans Candida Species Germ Tube Killer Toxin Phospholipase Activity 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • L. Krempl-Lamprecht
    • 1
  1. 1.The Clinic and Out-Patient Clinic of DermatologyTechnical University of MunichMunichThe Federal Republic of Germany

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