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Adhesion of Candida Albicans to Host Surfaces

  • L. J. Douglas
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 50)

Abstract

Colonization of host surfaces by the pathogenic Candida species depends on the ability of the fungi to adhere. Adhesion enables the organisms to resist the flushing action of the fluids that continuously bathe such surfaces. In the case of mucosal surfaces, epithelial cells with adherent microorganisms are repeatedly lost by desquamation and so the progeny of these organisms much attach to newly exposed cells if colonization is to continue. This host defence mechanism provides a selective pressure which may result in the elimination of less adhesive organisms. Adhesion is, therefore, the first step in the process leading to persistent colonization and infection, and the ability to adhere constitutes an important virulence factor.

Keywords

Adhesion Mechanism Buccal Cell Host Surface Extracellular Polymeric United Kingdom Introduction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • L. J. Douglas
    • 1
  1. 1.Department of MicrobiologyUniversity of GlasgowGlasgowUK

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