Transglucosylation Catalysed by the Exo-ß-Glucanase of Candida Albicans

  • P. A. Sullivan
  • G. W. Emerson
  • M. J. Broughton
  • H. J. Stubbs
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 50)


The β-1,3/1,6-glucan that constitutes 70% of the cell wall of Candida albicans 1 is qualitatively similar to the glucan of Saccharomyces cerevisiae but it contains higher proportions of branch points (7%) and β-1,6 linkages (43–50%)2.Cabib at al. 3 have reviewed the current understanding of the synthesis of the call wall. Linear chains of β-1,3 glucan are synthesized by a UDP-glucose synthetase located in the plasma membrane but nothing is known about the formation of β-1,6 oligosaccharide chains, branching or cross linking to other polymers. In this paper we describe a rapid transglucosylation reaction catalyzed by an exo-β-glucanase from C.albicans.


Candida Albicans Oligosaccharide Chain Glucosyl Unit Cell Wall Expansion Transferase Reaction 


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • P. A. Sullivan
    • 1
  • G. W. Emerson
    • 1
  • M. J. Broughton
    • 1
  • H. J. Stubbs
    • 1
  1. 1.Department of BiochemistryUniversity of OtagoDunedinNew Zealand

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