The Pathogenetic Role of Candida in Psoriasis
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Psoriasis is a chronic, recurrent and inflammatory skin disease. It is characterized by erythematous scaly patches on knees, elbows, sacral area and scalp. The etiopathogenesis of psoriasis is still unknown. Recent reports have suggested a role for the alternative complement pathway 1. Psoriasis may result from the interaction of yeasts and other microorganisms with an abnormally responsive alternative complement pathway 1,2. C. albicans is a potent activator of alternative complement pathway. This suggested that the yeast flora of gastrointestinal tract may play an important role in the etiopathogenesis of psoriasis.
KeywordsStool Sample Candida Species Pathogenetic Role Psoriatic Patient Inflammatory Skin Disease
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