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The Pathogenetic Role of Candida in Psoriasis

  • Ü. Soyuer
  • Ö. Aşçloğlu
  • E. Aktaş
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 50)

Abstract

Psoriasis is a chronic, recurrent and inflammatory skin disease. It is characterized by erythematous scaly patches on knees, elbows, sacral area and scalp. The etiopathogenesis of psoriasis is still unknown. Recent reports have suggested a role for the alternative complement pathway 1. Psoriasis may result from the interaction of yeasts and other microorganisms with an abnormally responsive alternative complement pathway 1,2. C. albicans is a potent activator of alternative complement pathway. This suggested that the yeast flora of gastrointestinal tract may play an important role in the etiopathogenesis of psoriasis.

Keywords

Stool Sample Candida Species Pathogenetic Role Psoriatic Patient Inflammatory Skin Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    E.W. Rosenberg and P.W. Belew, Microbial factors in psoriasis, Arch. Dermatol., 118: 143 (1982).PubMedCrossRefGoogle Scholar
  2. 2.
    N. Crutcher, E.W. Rosenberg, P.W. Bele et al., Oral nystatin in the treatmnet of psoriasis, Arch. Dermatol., 120: 435 (1984).PubMedCrossRefGoogle Scholar
  3. 3.
    D.W. Warnock, D.C.E. Speller, P.J. Finan et al., Antibodies to Candida species after operations o the large intestine: Observations on the association with the oral and faecal colonization, Sabouraudia, 17: 405 (1979).PubMedCrossRefGoogle Scholar
  4. 4.
    W. Wachowiak, G.V. Stryker, J. Marr et al., The occurence of monilia in relaton to psoriasis, Arch. Dermatol., 19: 713 (1929).CrossRefGoogle Scholar
  5. 5.
    H. Hänel, I. Menzel and H. Holzmann, Hohe Phospholipase A-Aktivität von Candida albicans aus Darm von Psoriatikern, Mykosen, 31: 451 (1988).Google Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Ü. Soyuer
    • 1
  • Ö. Aşçloğlu
    • 1
  • E. Aktaş
    • 1
  1. 1.Department of Dermatology, Faculty of MedicineErciyes UniversityKayseriTurkey

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