Adhesion of Candida to Murine Gastrointestinal Mucosa of Animals Treated with Anti-Cancer Therapy and Inhibition by a Chitin Derivative

  • H. Sandovsky-Losica
  • E. Segal
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 50)


It is well established that Candida albicans is an inhabitant of the gastrointestinal (GI) tract in a significant proportion of the normal population 20–65%1. In debilitated individuals, following various treatments such as broad spectrum antibiotics, irradiation or anti-cancer cytotoxic drugs, an increased colonization of the GI system is observed (56–75%)2.


Candida Albicans Spleen Weight Tissue Disk Untreated Control Mouse Chitin Derivative 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • H. Sandovsky-Losica
    • 1
  • E. Segal
    • 1
  1. 1.Department of Human Microbiology, Sackler School of MedicineTel-Aviv UniversityTel-AvivIsrael

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