Abstract
Extracellular matrix proteoglycans play an important role in main taining structural integrity and normal function of the arterial wall. These macromolecules provide structural links between fibrous and cellular elements, contribute to viscoelastic properties, regulate permeability and retention of plasma components through the matrix, control vascular cell growth, affect hemostasis and interact with lipoproteins (1,2). These functional properties indicate that proteoglycans are clearly involved in the pathogenesis of atherosclerosis.
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© 1990 Plenum Press, New York
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Srinivasan, S.R., Radhakrishnamurthy, B., Vijayagopal, P., Berenson, G.S. (1990). Proteoglycans, Lipoproteins, and Atherosclerosis. In: Malmendier, C.L., Alaupovic, P., Brewer, H.B. (eds) Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics. Advances in Experimental Medicine and Biology, vol 285. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5904-3_45
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DOI: https://doi.org/10.1007/978-1-4684-5904-3_45
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