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Transcriptional Regulation of the Human Apolipoprotein Genes

  • Vassilis I. Zannis
  • Dimitris Kardassis
  • Kinya Ogami
  • Margarita Hadzopoulou-Cladaras
  • Christos Cladaras
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 285)

Abstract

The transcription of eukaryotic genes is controlled by the interaction of regulatory gene sequences (promoter elements) with specific nuclear proteins (transcription factors) (1–3). The interaction of the transcription factors with the promoter elements controls: a) tissue specific gene expression (4–6); b) gene expression during differentiation and development (7,8); and c) gene expression in response to intracellular and extracellular stimuli such as hormones and metabolites (9–12).

Keywords

Promoter Element Chloramphenicol Acetyl Transferase Internal Deletion Footprint Area apoB Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Vassilis I. Zannis
    • 1
  • Dimitris Kardassis
    • 1
  • Kinya Ogami
    • 1
  • Margarita Hadzopoulou-Cladaras
    • 1
  • Christos Cladaras
    • 1
  1. 1.Section of Molecular Genetics Cardiovascular Institute Departments of Medicine and BiochemistryBoston University Medical CenterBostonUSA

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