Alcohol Dehydrogenase Gene Expression and Cloning of the Mouse χ-Like ADH

  • Howard J. Edenberg
  • Celeste J. Brown
  • Lucinda G. Carr
  • Wei-Hsien Ho
  • Man-Wook Hur
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 284)


Some of the differences between individuals in the metabolism of alcohol and in their susceptibility to alcoholism or its complications may be due to differences in the metabolism of ethanol. The amount of each different isozyme expressed will influence the overall alcohol dehydrogenase activity in a given tissue, and could play an important role in mediating or modulating the effects of ethanol. For these reasons, we have been studying the structure and expression of the mammalian alcohol dehydrogenases.


Alcohol Dehydrogenase Human Class Alcohol Dehydrogenase Activity ADH2 Promoter Alcohol Dehydrogenase Gene 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Howard J. Edenberg
    • 1
  • Celeste J. Brown
    • 1
  • Lucinda G. Carr
    • 1
  • Wei-Hsien Ho
    • 1
  • Man-Wook Hur
    • 1
  1. 1.Department of Biochemistry and Molecular BiologyIndiana University School of MedicineIndianapolisUSA

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