Reactivity of Enzyme Modification Reagents with Aldose Reductase and Aldehyde Reductase
Aldose reductase (EC 220.127.116.11) and aldehyde reductase (EC 18.104.22.168) are members of a broad family of NADPH-dependent reductases (Feldstead and Bachur, 1980). While the physiological role of either enzyme remains unknown, it is generally assumed that aldose reductase reduces aldose sugars to their respective sugar alcohols while aldehyde reductase reduces a broad range of aromatic and aliphatic aldehydes. Aldehyde reductase is also known as hexonate dehydrogenase EC 22.214.171.124) because of its ability to oxidize L-gulonic acid to glucuronic acid..
KeywordsAldose Reductase Aldose Reductase Inhibitor Desalt Column Carbonyl Reductase Aldehyde Reductase
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