Polymer Gels pp 309-317 | Cite as

Hydrophobic Weak Polybasic Gels: Factors Controlling Swelling Equilibria

  • Ronald A. Siegel
  • Bruce A. Firestone
  • Jose Cornejo Bravo
  • Barry Schwarz


The equilibrium and kinetic swelling properties of polymer gels are of considerable interest in the pharmaceutical field. Gels have been proposed as size selective extraction solvents1 and environmentally sensitive permeability barriers for a variety of pharmacologic agents.2,3 The use of gel mechanochemistry to drive an insulin pump is also under investigation.4


Ionic Strength Outer Solution Effective Dielectric Constant Donnan Equilibrium Polymer Volume Fraction 


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Ronald A. Siegel
    • 1
  • Bruce A. Firestone
    • 1
  • Jose Cornejo Bravo
    • 1
  • Barry Schwarz
    • 1
  1. 1.Departments of Pharmacy and Pharmaceutical ChemistryUniversity of CaliforniaSan FranciscoUSA

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