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Polymer Gels pp 271-285 | Cite as

Measuring Contact Stress with 19F-NMR Spectroscopy

  • Peter J. Basser

Abstract

Increased static contact stress is associated with tissue damage in vivo and in vitro. It could be caused by edema (for example, in normal hydrocephalus) or a growing tumor which displaces surrounding tissue. Measurement of contact stress is inherently invasive, however, it can be less traumatic with a sensor having no wires or leads. One goal of this chapter is to propose that NMR spectroscopy can perform the function of a telemetry system provided that an in-dwelling transducer can convert the desired physical quantity (such as applied stress) to an NMR detectable chemical change. Previously, it was observed that compressing polyelectrolyte gels could cause a redistribution of mobile ions that is measurable with NMR spectroscopy [1]. In the sensor described below, the applied stress is inferred from a non-invasive 19F-NMR spectroscopic measurement of pH.

Keywords

Applied Stress Contact Stress Dissociation State Hydrolyze Polyacrylamide External Bath 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Peter J. Basser
    • 1
  1. 1.Biomedical Engineering and Instrumentation ProgramNational Institutes of HealthBethesdaUSA

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