Biological Significance of Active Oxygen Species: In Vitro Studies on Singlet Oxygen-Induced DNA Damage and on the Singlet Oxygen Quenching Ability of Carotenoids, Tocopherols and Thiols

  • Paolo Di Mascio
  • Stephan P. Kaiser
  • Thomas P. A. Devasagayam
  • Helmut Sies
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 283)


Reactive oxygen species have been in focus for some time now, and there are several reviews on this topic. since our contribution to Biological Reactive Intermediates III (Wefers and Sies, 1986), work from our laboratory has been presented comprehensively (Sies, 1986, 1988; Ishikawa and Sies, 1989). Further, the biochemistry of oxygen toxicity has been presented (Cadenas, 1989).


Chlorophyll Glutathione Retina Methionine Bilirubin 


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Paolo Di Mascio
    • 1
  • Stephan P. Kaiser
    • 1
  • Thomas P. A. Devasagayam
    • 1
  • Helmut Sies
    • 1
  1. 1.Institut für Physiologische Chemie IUniversity of DüsseldorfDüsseldorfWest Germany

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