Structure-Activity Relationships of Acrylate Esters: Reactivity Towards Glutathione and Hydrolysis by Carboxylesterase in Vitro
Acrylate esters are high volume, versatile chemicals in the plastics industry. Long)term industrial exposure to these esters has caused contact hypersensitivity and dermatitis, while laboratory studies have shown these esters to be strong irritants, sensitizers, clastogens, and some have been shown to be weak carcinogens (Andrews and Clary, 1986). Numerous members make up this class of chemicals sharing an α, β- unsaturated ester structure. The individual members differ from each other due to structural features added onto the α, β-unsaturated ester.
KeywordsMethyl Acrylate Butyl Acrylate Ethyl Acrylate Ethyl Methacrylate Butyl Ester
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