Cyanide Liberation and Oxidative Stress by Organothiocyanates, Organonitriles and Nitroprusside in Isolated Hepatocytes

  • Sahar Elguindi
  • Peter J. O’Brien
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 283)


Organothiocyanates and organonitriles are effective insecticide and fungicide chemicals. Glutathione-S-transferases may play a role in the liberation of HCN from organothiocyanates whereas mixed-function oxidases may play a role in HCN liberation from various organonitriles [Ohkawa et al., 1972].


Sodium Nitroprusside Potassium Cyanide Cyanide Liberation Sodium Thiocyanate Effective Insecticide 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Sahar Elguindi
    • 1
  • Peter J. O’Brien
    • 1
  1. 1.Faculty of PharmacyUniversity of TorontoTorontoCanada

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