Abstract
The toxic effects of many xenobiotics are very often not due to the parent compound itself but to reactive intermediates or metabolites formed in situ inside the cell. These reactive species may bind covalently to cell proteins leading to various cell disorders and eventually to toxic effects.
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© 1991 Plenum Press, New York
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Mansuy, D. (1991). Formation of Reactive Metabolites and Appearance of Antiorganelle Antibodies in Man. In: Witmer, C.M., Snyder, R.R., Jollow, D.J., Kalf, G.F., Kocsis, J.J., Sipes, I.G. (eds) Biological Reactive Intermediates IV. Advances in Experimental Medicine and Biology, vol 283. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5877-0_14
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DOI: https://doi.org/10.1007/978-1-4684-5877-0_14
Publisher Name: Springer, Boston, MA
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