Neural Activity of the Basal Ganglia in Parkinson’s Disease Studied by Depth Recording and Pet Scan
The basal ganglia is certainly one of the major centers of the central nervous system controlling voluntary movement and posture1, but its precise role is still far from understanding. Only experimental studies in monkeys with various conditioned voluntary movements or with experimentally produced involuntary movements were carried out to observe neural activities of the basal ganglia associated with these particular conditions.
KeywordsBasal Ganglion Essential Tremor Globus Pallidus Positron Emission Tomog Depth Recording
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- 1.M.D. DeLong and A.P. Georgopoulos, Motor function of of the basal ganglia. in; “Handbook of Physiology, The Nervous System II”, V.B. Brooks, ed., Amer. Physiol. Soc., Bethesda (1981) pp 1017–1061.Google Scholar
- 2.C. Ohye, A new aspect of parkinsonian rigidity and tremor (in japanese). Internal Med., 63: 831–836 (1989).Google Scholar
- 3.M. Hirato, Y. Kawashima, T. Shibasaki, T. Shibazaki, and C. Ohye, Cerebral metabolism in parkinson’s disease-Comparison between rigidity and tremor (in japanese). Stereotactic Surgery, (in press).Google Scholar
- 4.M. Hirato, Y. Kawashima, T. Shibazaki, T. Shibasaki and C. Ohye, Pathophysiology of parkinsonian rigidity (in Japanese). Stereo-tactic Surgery, (in press).Google Scholar
- 5.T. Shibasaki, Analysis of human cerebral function using positron emission tomography (in japanese). Progr. Neurosci., 28: 211–228 (1986).Google Scholar
- 6.C. Ohye, Selective Thalamotomy for Movement Disorders: Micro-recording Stimulation, Techniques and Results, in; Modern Stereotactic Surgery“, L.D. Lunsford, ed., Martius Nijhoff Pub., Boston, (1988) pp 315–331.Google Scholar
- 8.Y. Kawashima, M. Matsumura, M. Hirato, T. Shibazaki, C. Ohye and H. Nakajima, Application of CT and MRI for stereotactic functional neurosurgery (in Japanese). Stereotctic Surgery, (in press).Google Scholar
- 12.M.A. Sambrook, A.R. Crossman, I. Mitchell, R.G. Robertson, C.E. Clarke and S. Boyce, The basal ganglia mechanisms mediating primate models of movement disorders. in: “Neural Mechanisms in disorders of movement“, A.R. Crossman and M.A. Sambrook, eds., John Libbey, London-Paris, (1989) pp 123–144.Google Scholar
- 13.I. Mitchell, C.E. Clarke, S. Boyce, R.G. Robertson, D. Peggs, M.A. Sambrook and A.R. Grossman, Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience, 32: 213–226 (1989).PubMedCrossRefGoogle Scholar
- 15.M. Filion, L. Tremblay and P.J. Bedard, Excessive and unselective response of medial pallidal neurons to both passive movement and striatal stimulation in monkeys with MPTP-induced parkinsonism. in: “Neural mechanisms in disorders of movement. A.R. Crossman and M.A. Sambrook, eds., John Libbey, London-Paris, (1989) pp 157–164.Google Scholar
- 16.D.J. Brooks and R.S.J. Frackowiak, PET and movement disorders. J. Neurol. Neurosurg. Psychiat. special suppl.: 68–77 (1989).Google Scholar