Dye-Coupling in the Neostriatum of the Rat

  • Carlos Cepeda
  • John P. Walsh
  • Chester D. Hull
  • Nathaniel A. Buchwald
  • Michael S. Levine
Part of the Advances in Behavioral Biology book series (ABBI, volume 39)


Morphologically, gap junctions are intermembranous channels between cells thought to mediate electrotonic transmission and to serve as a passage for small molecules in the CNS (for a review see Sotelo and Korn, 1978). After the discovery that the fluorescent dye Lucifer yellow crosses gap junctions to label adjacent cells (Stewart, 1978), dye-coupling was used as indirect evidence for the presence of gap junctions. Dye-coupling occurs in several neural areas, including the hippocampus (Knowles et el., 1982; MacVicar et al., 1982), the neocortex (Connors et al., 1983; Gutnick and Prince, 1981) and the hypothalamus (Andrew et al., 1981; Hatton et al., 1987). In parallel ultrastructural studies, gap junctions have been shown to be present in some of these structures (Sloper and Powell, 1978; Sotelo and Korn, 1978).


Horizontal Cell Dopamine Concentration Lucifer Yellow Postnatal Development Electrolytic Lesion 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Carlos Cepeda
    • 1
  • John P. Walsh
    • 1
  • Chester D. Hull
    • 1
  • Nathaniel A. Buchwald
    • 1
  • Michael S. Levine
    • 1
  1. 1.Mental Retardation Research CenterUniversity of CaliforniaLos AngelesUSA

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