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The Ultrastructural Chemoanatomy of the Basal Ganglia: 1984–1989. I. The Neostriatum

  • Pedro Pasik
  • Tauba Pasik
  • Gay R. Holstein
Part of the Advances in Behavioral Biology book series (ABBI, volume 39)

Abstract

Our last review on the ultrastructural chemoanatomy of the basal ganglia (Pasik et al., 1986) covered the articles published through part of 1984. In our concluding remarks, we emphasized that the significant gaps in our knowledge at the time, could be expected to be filled by the application of new techniques that were just beginning to show some success. They were: (1) the development of antibodies directed against small molecules such as the neuroactive substances, as opposed to their synthesizing enzymes; (2) the use of more subtle markers such as ferritin or gold particles, which do not obscure the subcellular details of labeled structures; and (3) the possibility of differentially visualizing more than one substance in the same preparation, thereby improving the chances for the discovery of the interactions which characterize the neuronal circuits operating in the basal ganglia.

Keywords

Axon Initial Segment Proximal Dendrite Striatal Cell Dendritic Shaft Asymmetric Synapse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

ACh

Acetylcholine

DBH

Dopamine beta hydroxylase

CBP

Calcium-binding proteins

CCK

Cholecystokinin

CGRP

Calcitonin gene-related peptide

ChAT

Choline acetyltransferase

CP

Caudate-putamen

DA

Dopamine

ENK

Enkephalins

5-HT

Serotonin

GABA

Gamma aminobutyric acid

GAD

Glutamate decarboxylase

GLU

Glutamate

GP

Globus pallidus

HRP

Horseradish peroxidase

NADPH-D

Nicotinamide adenine dinucleotide phosphate-diaphorase

NN

Neuromedin-N

NPY

Neuropeptide Y

NT

Neurotensin

PPN

Pedunculopontine nucleus

SN

Substantia nigra

SNc

Substantia nigra, pars compacta

SNl

Substantia nigra, pars lateralis

SNr

Substantia nigra, pars reticulata

SP

Substance P

SS

Somatostatin

SThN

Subthalamic nucleus

TH

Tyrosine hydroxylase

VIP

Vasoactive intestinal polypeptide

VTA

Ventral tegmental area

WGA

Wheat germ agglutinin

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References

  1. A single list of references is given at the end of the following chapter for both articles.Google Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Pedro Pasik
    • 1
    • 2
  • Tauba Pasik
    • 1
  • Gay R. Holstein
    • 1
    • 2
  1. 1.Departments of Neurology Mount Sinai School of MedicineCUNYNew YorkUSA
  2. 2.Cell Biology-Anatomy Mount Sinai School of MedicineCUNYNew YorkUSA

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