Subthalamic Nucleus Afferents: Anatomical and Immunocytochemical Features

  • M. B. Carpenter
  • A. Jayaraman
Part of the Advances in Behavioral Biology book series (ABBI, volume 39)


The subthalamic nucleus (STN) may be the only CNS site at which a discrete destructive or biochemical lesion consistently results in a characteristic contralateral dyskinesia in man and monkey (Whittier,1947; Carpenter et al.,1950; Hammond et al.,1979). The STN, a hypothalamic derivative, consists of a single population of cells, virtually all of which are projections neurons (Richter, 1965; Van der Kooy and Hattori,1980). The neurotransmitter of STN neurons is unknown, but GABA immunoreactive terminals surround STN neurons in the monkey (Smith et al., 1987).


Globus Pallidus Subthalamic Nucleus Terminal Field Efferent Projection Pallidal Neuron 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • M. B. Carpenter
    • 1
    • 2
  • A. Jayaraman
    • 1
    • 2
  1. 1.Uniformed Services UniversityBethesdaUSA
  2. 2.Louisiana State UniversityNew OrleansUSA

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