Selective Excitation Techniques for Water Suppression in One-and Two-Dimensional NMR Spectroscopy

  • Vladimír Sklenár
Part of the Basic Life Sciences book series (BLSC, volume 56)


The measurement in non-deuterated water solutions is a long-standing problem in the pulse Fourier transform NMR spectroscopy. Very large signal from the water protons (c ~100 M) introduces serious problems which arise from the limited ADC (analog-to-digital converter) resolution, nonlinearities in the detection channel and from computer data manipulations. As a result, special experimental techniques which suppress the intense water resonance are required to overcome the NMR system limitations. History of the development of special experimental tools began in the middle seventies with the introduction of the well known 214 pulse sequence by A.G. Redfield et al. (1975). Despite the great effort and substantial contributions in the following years the field remained open for further development.


Selective Excitation Water Suppression Water Resonance Imino Proton Excitation Profile 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Vladimír Sklenár
    • 1
  1. 1.Institute of Scientific InstrumentsCzechoslovak Academy of SciencesBrnoCzechoslovakia

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