Studies of Evolving Carbohydrate Metabolism invivo by 13C Surface-Coil NMR Spectroscopy
The capability of NMR spectroscopy to study biological systems noninvasively was extended to whole animal applications by the introduction of the surface-coil receiver by Ackerman et al. (1980). While this first demonstration utilized a 31P-tuned receiver for the detection of phosphorus signals, the technique has been extended to other nuclides, including proton ( 1H) and fluorine (19F), and, in conjunction with proton-decoupling, carbon ( 13C).
KeywordsGlycogen Synthesis Hepatic Glycogen Substrate Mixture Glycogen Particle Label Glucose
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- Cohen, S. M., Shulman, R. G., and McLaughlin, A. C., 1979, ibid, 76:4808.Google Scholar
- Kuwajima, M., Newgard, C. B., Foster, D. W., and McGarry, J. D., 1984, J. Biol. Chem., 261:8849–8853.Google Scholar
- Reo, N. V., Ewy, C. S., Siegfried, B. A., and Ackerman, J. J. H., 1984a, J. Magn. Reson., 58:76–84.Google Scholar