Heterogeneity of Intact Collagen by Solid State Multinuclear Magnetic Resonance

  • Yukio Hiyama
  • Dennis A. Torchia
Part of the Basic Life Sciences book series (BLSC, volume 56)


Molecular structure of collagen by X-ray diffraction and electron microscopy suggests heterogeneity of the molecule in the gap and overlap regions (Fig. 1). Previous 13C NMR data of collagen showed no heterogeneity (Sarkar et al., 1983; Torchia et al., 1985). Therefore we have designed the following two experiments.


Hydrogen Exchange Chemical Shift Anisotropy Tendon Collagen Chemical Shift Tensor Principal Frequency 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Yukio Hiyama
    • 1
  • Dennis A. Torchia
    • 1
  1. 1.Bone Research Branch National Institute of Dental ResearchNational Institutes of HealthBethesdaUSA

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