N-CAM is a Target Cell Surface Antigen for the Purification of Muscle Cells for Myoblast Transfer Therapy
Since the introduction of the monoclonal antibody (McAb) method by Kohler and Milstein over ten years ago, a major goal of cell biologists has been to define and characterize lineage and cell type specific antigens that may allow the identification and manipulation of specific cells. While in principle it is possible to prepare McAbs to any subcellular compartment or organelle, a large amount of effort has gone into the identification of cell surface antigens. There are a number of sound reasons for this preference.
KeywordsNeural Cell Adhesion Molecule Cell Surface Antigen Human Myoblast Human Muscle Cell Transfer Therapy
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