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Regeneration of Skeletal Muscle Fibers after Necrosis

  • Stirling Carpenter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 280)

Abstract

I am going to review the normal process of regeneration after necrosis in skeletal muscle and compare it with what happens in Duchenne dystrophy. Dr. Karpati and I have devised an experimental method for producing a focal lethal injury of skeletal muscle qells in which the sequence of steps can be closely followed. We call it experimental micropuncture injury, because the muscle cells are transfixed by a fine tungsten wire with a 10µm tip. All fibers that are pierced go on to necrosis.

Keywords

Satellite Cell Duchenne Dystrophy Basal Lamina Muscle Regeneration Neural Cell Adhesion Molecule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Stirling Carpenter
    • 1
  1. 1.Montreal Neurological InstituteMcGill UniversityMontrealCanada

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