Exanthem Subitum and Human Herpesvirus 6 (HHV-6) Infection
A novel human herpesvirus, now named human herpesvirus 6 (HHV-6), has been isolated independently by several groups from patients with lymphocytic disorders (1–5). This virus was initially named “human B lymphotropic virus,” because it infected B lymphocytes (1). However, it was later found mainly to infect and replicate in lymphocytes of T-cell lineage (2, 3, 6, 7). Preliminary characterization of HHV-6 indicated that the virus was antigenically and genetically distinct from other human herpesviruses (cytomegalovirus [CMV], herpes simplex virus types 1 and 2 [HSV-1 and HSV-2], varicella-zoster virus [VZV], and Epstein-Barr virus [EBV]) (1, 4).
KeywordsHerpes Simplex Virus Type Southern Blot Hybridization Human Herpesvirus Throat Swab Convalescent Phase
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