Replication of Human Herpesvirus 6 (HHV-6): Morphological Aspects

  • Shiro Nii
  • Mariko Yoshida
  • Fumio Uno
  • Takeshi Kurata
  • Kazuyoshi Ikuta
  • Koichi Yamanishi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 278)


Human herpesvirus 6 (HHV-6) was first isolated by Salahuddin et al. (1) from the peripheral-blood leukocytes of six patients with associated lymphoproliferative disorders, and subsequently by Lopez et al. (2) and other research groups (3, 4) from individuals seronegative as well as individuals seropositive for human immunodeficiency virus (HIV). Yamanishi et al. (5) probably isolated a different strain of the same virus from the peripheral-blood lymphocytes of patients with exanthem subitum.


Human Immunodeficiency Virus Human Herpesvirus Viral Core Nuclear Vacuole Perinuclear Cisterna 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Shiro Nii
    • 1
  • Mariko Yoshida
    • 1
  • Fumio Uno
    • 1
  • Takeshi Kurata
    • 2
  • Kazuyoshi Ikuta
    • 3
  • Koichi Yamanishi
    • 4
  1. 1.Department of VirologyOkayama University Medical SchoolOkayama, Okayama 700Japan
  2. 2.Department of PathologyNational Institute of HealthShinagawa-ku, Tokyo 141Japan
  3. 3.Department of Cellular Immunology, Institute of Immunological ScienceHokkaido UniversitySapporo 060Japan
  4. 4.Department of Virology, Research Institute for Microbial DiseasesOsaka UniversitySuita, Osaka 565Japan

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