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Prevalence of Specific Antibodies to Herpes Simplex Virus Type 2 as Revealed by an Enzyme-linked Immunoassay and Western Blot Analysis

  • Karen V. Spiezia
  • Bruce J. Dille
  • Isa K. Mushahwar
  • Lemma Kifle
  • Greg F. Okasinski
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 278)

Abstract

Herpes simplex virus (HSV) infections are characterized by a wide variety of symptoms ranging from asymptomatic infection to systemic involvement including encephalitis (1, 2). Two problems complicating identification of individuals infected with genital HSV are asymptomatic acquisition of the virus and insensitive viral detection methods (3, 4). As a result, a substantial population exists which is unaware of having an HSV infection yet is harboring latent virus. The implications of this population of infected but unaware people are significant for transmission to sexual partners or to neonates during birth.

Keywords

Herpes Simplex Virus Herpes Simplex Virus Type Genital Herpes Herpes Simplex Virus Infection Polystyrene Bead 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Karen V. Spiezia
    • 1
  • Bruce J. Dille
    • 1
  • Isa K. Mushahwar
    • 1
  • Lemma Kifle
    • 2
  • Greg F. Okasinski
    • 2
  1. 1.Infectious Disease and Immunology ResearchAbbott LaboratoriesAbbott ParkUSA
  2. 2.Molecular Biology DepartmentAbbott LaboratoriesAbbott ParkUSA

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