Acetylcholinesterase of Cerebral Microvessels Changes in Alzheimer’s Disease
Acetylcholinesterase (AChE) is histochemically demonstrable in capillary basement membranes of brain regions that contain relatively high AChE activity in their neuronal elements (Kreutzberg et al., 1975). Moreover, AChE might possibly be coupled with choline transport in microvessels isolated from the rat forebrain (Shimon et al., 1989). However, AChE activity has not been studied biochemically in microvessels isolated from human brains.
KeywordsAChE Activity Alzheimer Brain Sucrose Density Gradient Acetylcholinesterase Activity Sedimentation Coefficient
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