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Computer-Aided Quantitative Analysis of the Distribution of Catecholamine-Containing Fibers in the Primate Prefrontal Cortex

  • Hiroko Matsumura
  • Minoru Narita
  • Keiji Satoh
  • Ikuko Nagatsu
Part of the Advances in Behavioral Biology book series (ABBI, volume 38A)

Abstract

The primate prefrontal cortex is densely innervated by midbrain dopamine (DA) neurons. Although the function of this mesocortical DA system is not known, it is believed that this catecholamine (CA) fiber system might be involved in certain mental disorders. In the present study, we investigated the CA innervation of the monkey prefrontal cortex by tyrosine hydroxylase (TH) immunohistochemistry, which is thought to be a reliable method to study cortical DA fibers.1 The density of TH-containing fibers was measured by a computer-aided image analysis technique.

Keywords

Prefrontal Cortex Tyrosine Hydroxylase Cortical Layer Immunoreactive Fiber Laminar Distribution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Hiroko Matsumura
    • 1
  • Minoru Narita
    • 1
  • Keiji Satoh
    • 1
  • Ikuko Nagatsu
    • 1
  1. 1.Dept. of Psychiat., Shiga Univ. of Medical Science, Otsu and Dept. of Anatomy, School of MedicineFujita-Gakuen Health Univ.ToyoakeJapan

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