Topographical Distribution, Fine Structure of Component Fibrils, and Immunoreactivity of Neuronal Inclusions in Alzheimer’s, Parkinson’s, and Pick’s Diseases
Neurofibrillary tangles(NFT’s), Pick bodies(PB’s), and Lewy bodies(LB’s) are filamentous neuronal inclusions that individually characterize different diseases. The distribution pattern, fine structure of the component fibrils, and immunoreactivity of these inclusions seem to share much in common with one another1–4. However, it has not been fully documented what similarity and dissimilarity can exist among them. It is not yet clear whether NFT’s in cases of Alzheimer’s dsease, Down’s syndrome, and myotonic dystrophy show an identical immunoreactivity. The purpose of this study was to elucidate these points.
KeywordsNeurofibrillary Tangle Sympathetic Ganglion Myotonic Dystrophy Pontine Nucleus Nucleus Dorsal Vagal
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- 1.A. Probst, B. H. Anderton, J. Ulrich, R..Kohler, J. Kahn, and P. U. Heitz, Pick’s disease: an immunocytochemical study of neuronal changes, Acta Neuropathol. 60: 175 (1983).Google Scholar