Role of Brain Monoamines and Other Neurotransmitters in Normal and Pathological Aging

  • Arvid Carlsson
Part of the Advances in Behavioral Biology book series (ABBI, volume 38A)


Although the life span of living organisms is ultimately determined by their genes, environmental factors are also important. The well-known “squaring off” of human survival curves illustrates this interaction. Also the general health of aged people appears to improve continuously, and this includes the mental health (Svanborg et al. 1986). In fact, the picture of senile dementia, i.e. “second childishness, mere oblivion” (quoted from “As you like it”), was familiar to William Shakespeare, even though very few people in his time reached the age when this condition starts to become prevalent in our time. This is encouraging, because it strengthens the hope that further environmental improvement as well as therapeutic/prophylactic measures will prove successful.


Dopaminergic Neuron Dopaminergic System Quinolinic Acid Senile Dementia Noradrenergic System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Arvid Carlsson
    • 1
  1. 1.Department of PharmacologyUniversity of GöteborgGöteborgSweden

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