A Unifying Hypothesis on the Etiology of Alzheimer’s Disease

  • Zaven S. Khachaturian
Part of the Advances in Behavioral Biology book series (ABBI, volume 38A)


In recent years, it has become increasingly evident that the fundamental scientific issues concerning the etiology of Alzheimer’s disease (AD) should focus on the search for mechanisms of cell dysfunction and selective neuronal loss. It is now well established that the structural and functional changes in neurons occur in specific regions of the AD brain.


Selective Neuronal Loss Selective Cell Death Calcium Hypothesis Rational Treatment Strategy Calcium Messenger System 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Zaven S. Khachaturian
    • 1
  1. 1.Neurobiology and Neuropsychology of Aging Program National Institute on AgingNational Institutes of HealthUSA

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