Effects of Destruction of Nucleus Basalis Meynert on Operant Study and Neurotransmitters in Rats
In senile dementia of the Alzheimer type (SDAT), it has already been reported that the activity of neurotransmitters1–3 and number of cells in the nucleus basalis Meynert (nbM)4 are decreased. The purpose of our study was to evaluate changes in and correlation between the activity of neurotransmitters and response of ibotenic acid-lesioned WKY rats (a model of Alzheimer’s disease) in an operant study.
KeywordsNucleus Basalis Alzheimer Disease Patient Alzheimer Model Ibotenic Acid Choline Acetyl
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