Regulation of Neocortical Electrical Activity by Cholinergic and Noradrenergic Systems

  • P. RiekkinenJr.
  • J. Sirviö
  • P. Riekkinen
Part of the Advances in Behavioral Biology book series (ABBI, volume 38A)


Cognitive impairment associated with aging and an early stage of Alzheimer’s disease (AD) may be related to changes in the cholinergic projections from the basal forebrain to the neocortex and hippocampus (2,4). The maintenance of vigilance, the capacity to allocate attention and sharpness of memory are adversely affected during aging.


Basal Forebrain Noradrenergic System ChAT Activity Ibotenic Acid Delta Power 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • P. RiekkinenJr.
    • 1
  • J. Sirviö
    • 1
  • P. Riekkinen
    • 1
  1. 1.Department of NeurologyUniversity of KuopioKuopioFinland

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