Generating and Controlling Multiparameter Data Bases for Biochemical Correlates of Disorders
Perhaps the most powerful potential use of multiparameter biochemical data bases in studies of degenerative disorders is the unique discrimination of categories. The technology of Coulometric Array Electrode Systems (CEAS) can automatically resolve approximately 400 compounds from biological samples at the picogram level. Among these are tyrosine and tryptophan derived neurotransmitters, precursors, metabolites, conjugates and cofactors, certain purines, pterins and neuropeptides. This capability offers the promise of generating enough relevant data to describe disorders.
KeywordsDopamine Tyrosine Tryptophan Purine Monoamine
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