A Presynaptic Action of Glutamate on Cone Photoreceptors
The photoreceptors of lower vertebrates are thought to use glutamate as a neurotransmitter (Miller and Schwartz, 1983). The neurotransmitter actions of glutamate in the outer retina are well documented. Glutamate gates channels in postsynaptic bipolar (Attwell et al., 1987; Miller and Slaughter, 1986; Nawy and Copenhagen, 1987), and horizontal cells (Slaughter and Miller, 1983; Ishida et al., 1984). These neurotransmitter actions of glutamate may be terminated in part by electrogenic transport of glutamate into retinal glial (Müller) cells (Brew and Attwell, 1987).
KeywordsReversal Potential Horizontal Cell Patch Pipette External Sodium Bath Perfusion
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- Attwell, D., Mobbs, P., Tessier-Lavigne, M., and Wilson, M., 1987, Neurotransmitter-induced currents in retinal bipolar cells of the axolotl, Ambystoma mexicanum, J.Physiol., 387:125.Google Scholar
- Kaneko, A., and Tachibana, M., 1987, Effects of L-glutamate on isolated turtle photoreceptors, ARVO Abstracts, Invest. Opthalmol. Vis. Sci.(Suppl)., 28:50.Google Scholar
- Thieffrey, M., Bruner, J., and Personne, P., 1979, The presynaptic action of L-glutamate at the crayfish neuromuscular junction, J. Physiol., Paris, 75:635.Google Scholar