Studies on the Mechanism of Action of the Mitochondrial Energy-Linked Nicotinamide Nucleotide Transhydrogenase

  • Mutsuo Yamaguchi
  • Youssef Hatefi


This is a brief summary of the recent work of our laboratory on the structure and function of a unique energy-transducing enzyme of mammalian mitochondria, the nicotinamide nucleotide transhydrogenase (TH) (see 1,2 for reviews).


Conformation Change Cyanogen Bromide Proton Translocation Proton Uptake Scripps Clinic 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Mutsuo Yamaguchi
    • 1
  • Youssef Hatefi
    • 1
  1. 1.Division of Biochemistry Department of Molecular and Experimental MedicineResearch Institute of Scripps ClinicLa JollaUSA

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