Do Hydrogen Ions Serve as Bioenergetic Messengers in Yeast?
It was in the late fifties1 and early sixties2 that the idea dawned upon the scientific community that cations, in particular sodium ions, can form a concentration-plus-potential gradient across cell membranes which can be used for driving the (secondary) transport of amino acids and sugars in the intestinal mucosa3 and renal tubules4 as well as in ascites cells.5 The “sodium pump”, subsequently shown to be identical with the Na,K-adenosinetriphosphatase6,7 was the magic wand of many animal physiologists for years to come, helping them to explain the conversions of energy taking place in animal cell membranes.
KeywordsHeavy Water Accumulation Ratio Suspension Density Magic Wand Yeast Plasma Membrane
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