Branched Chain Amino Acids in the Treatment of Hepatic Encephalopathy

  • Filippo Rossi-Fanelli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 272)


To understand the role that branched chain amino acids (BCAA) may play in the pathogenesis and treatment of hepatic encephalopathy (HE) and the consequent relevance they may assume in the nutritional approach to a patient with chronic liver failure (CLF) we must carefully consider three main aspects:
  1. 1.

    The mechanisms leading to the characteristic alteration of the plasma amino acids (AA) pattern observed in CLF.

  2. 2.

    The role that changes in plasma AA play in the pathogenesis of HE.

  3. 3.

    The peculiar metabolic activities of BCAA.



Hepatic Encephalopathy Branch Chain Amino Acid Hepatic Coma Chronic Liver Failure Amino Acid Infusion 


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Filippo Rossi-Fanelli
    • 1
  1. 1.Laboratory of Clinical Nutrition 3rd Department of Internal MedicineUniversity of Rome “La Sapienza”Italy

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