Background Paper Advances in the Study of MHV Infection of Mice

  • Shigeru Kyuwa
  • Stephen Stohlman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 276)


Since the last International Coronavirus Meeting a number of very intriguing papers have appeared. These papers have provided insight into what continues to be a very exciting and complex interaction between MHV strains and their natural hosts and include studies of viral tropism, pathogenesis, the role of immune system and genetic factors. MHV infections in mice have been studied mainly as models of viral hepatitis (4,7,9,11,13) and both acute and chronic viral infection of the central nervous system (CNS) (2,5,6,8,15–17,19,20).


Central Nervous System Viral Hepatitis Demyelinating Disease Central Nervous System Infection Chronic Viral Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Shigeru Kyuwa
    • 1
  • Stephen Stohlman
    • 1
  1. 1.Departments of Neurology and MicrobiologyUniversity of Southern California School of MedicineLos AngelesUSA

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