Background Paper Advances in the Study of MHV Infection of Mice
Since the last International Coronavirus Meeting a number of very intriguing papers have appeared. These papers have provided insight into what continues to be a very exciting and complex interaction between MHV strains and their natural hosts and include studies of viral tropism, pathogenesis, the role of immune system and genetic factors. MHV infections in mice have been studied mainly as models of viral hepatitis (4,7,9,11,13) and both acute and chronic viral infection of the central nervous system (CNS) (2,5,6,8,15–17,19,20).
KeywordsCentral Nervous System Viral Hepatitis Demyelinating Disease Central Nervous System Infection Chronic Viral Infection