Analysis of Different Probe-Labeling Systems for Detection by Hybridization of Bovine Coronavirus

  • J. A. Verbeek
  • S. Dea
  • P. Tijssen
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 276)


Several methods for the detection of bovine Coronavirus (BCV) in clinical specimens have been developed (1–5). The notoriously difficult diagnosis by EM has recently been improved by the use of immunogold (3), whereas other methods have been described, based on serological detection (2,5) or on the hemagglutinating capacity of the virus (6,7). Even though increased specificity in immunological detection assays can be obtained using monoclonal antibodies, sensitivity and detectability still remain to be improved.


Clinical Specimen cDNA Insert Comptes Rendus Acad Bovine Coronavirus Acid Guanidium 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • J. A. Verbeek
    • 1
  • S. Dea
    • 1
  • P. Tijssen
    • 1
  1. 1.CRMC - Institute Armand-FrappierUniversity of QuebecLaval-des-RapidesCanada

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