Sequence Comparisons of the 3′ End of the Genomes of Five Strains of Avian Infectious Bronchitis Virus

  • Ellen W. Collisson
  • Anna K. Williams
  • Ray Vonder Haar
  • Wang Li
  • Loyd W. Sneed
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 276)


Avian infectious bronchitis virus (IBV) causes an acute, highly contagious respiratory disease of chickens characterized by tracheal rales, coughing and sneezing1. The disease was first described in 1931 by Schalk and Hawn1 and since that time, many strains have been defined2,3. These strains vary widely in virulence and tissue tropism. A number of serologically distinguishable strains of infectious bronchitis virus have been isolated from poultry in the U.S.A. Of the strains included in this study, Beaudette, Conn, and Ark DPI 75 are vaccine strains, Gray and AustT are known to be nephropathogenic causing limited respiratory disease, and infections with Ark99, Mass41 and a Japanese strain (KB8523) are generally thought to result in severe respiratory disease in the absence of nephritis and nephrosis4.


Noncoding Region Infectious Bronchitis Virus Nucleocapsid Protein Tissue Tropism Japanese Strain 
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  1. 1.
    A. F. Schalk, and M. C. Hawn, An apparantly new respiratory disease of baby chicks, JAVMA. 78:418–422 (1931).Google Scholar
  2. 2.
    J. H. Darbyshire, J. G. Rowell, J. K. A. Cook, and R. W. Peters,Taxonomic studies on strains of avian infectious bronchitis virus using neutralization tests in tracheal organ cultures, Arch.Virol. 61:227–238 (1979).PubMedCrossRefGoogle Scholar
  3. 3.
    S. R. Hopkins, Serologic comparisons of strains of infectious bronchitis using plaque-purified isolates, Avian Pis. 18:231–239 (1974).CrossRefGoogle Scholar
  4. 4.
    R. B. Cumming, The etiology of uremia of chickens, Aust.Vet.J. 39:145–147 (1963).CrossRefGoogle Scholar
  5. 5.
    M. Boursnell, M. Binns, I. Foulds, and T. Brown, Sequences of the nucleocapsid genes from two strains of avian infectious bronchitis virus, J.Gen.Virol. 66:573–580 (1985).PubMedCrossRefGoogle Scholar
  6. 6.
    S. Shizuyo, S. Seiji, T. Okabe, M. Nakai, and N. Sasaki, Cloning and sequencing of genes encoding structural proteins of avian infectious bronchitis virus, Virology 165: 589–595 (1988).CrossRefGoogle Scholar
  7. 7.
    L. Wang, M. C. Kemp, P. Roy, and E. Collisson, Tissue tropism and target cells of Bluetongue virus in the chicken embryo. J.Virol. 62:887–893 (1988).PubMedGoogle Scholar
  8. 8.
    U. Gubler and B. J. Hoffman, A simple and very efficient method for generating cDNA libraries, Gene 25:263–269 (1983).PubMedCrossRefGoogle Scholar
  9. 9.
    S. L. Berger and A. R. Kimmel, Guide to Molecular Cloning Techniques; in Meth. in Enzym. 152 (1987) .Google Scholar
  10. 10.
    E. Y. Chen and P. H. Seeburg, Supercoil sequencing: A fast and simple method for sequencing plasmid DNA, DNA 4(2):165–170 (1985).PubMedCrossRefGoogle Scholar
  11. 11.
    F. Sanger, S. Nicklen, A. R. Coulson, DNA sequencing with chain-terminating inhibitors. PNAS USA 74:5463–5467 (1977).PubMedCrossRefGoogle Scholar
  12. 12.
    L. Sneed, G. Butcher, L. Wang, M. Kemp, and E. Collisson, Protein and RNA comparisons of several strains of IBV. Southern Conference on Avian Disease. (March 1987)Google Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Ellen W. Collisson
    • 1
  • Anna K. Williams
    • 1
  • Ray Vonder Haar
    • 2
  • Wang Li
    • 1
  • Loyd W. Sneed
    • 1
  1. 1.Department of Veterinary MicrobiologyTexas A&M UniversityCollege StationUSA
  2. 2.Department of BiologyTexas A&M UniversityCollege StationUSA

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