Background Paper Aspects of Coronavirus Evolution

  • D. Cavanagh
  • T. D. K. Brown
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 276)


The word “evolution” usually evokes thoughts of events which occurred in the distant past, but it is self-evidently an ongoing process. The application of intense selective pressure, for example by the wide-spread use of vaccination, and also the transport of infected animals over large distances may have contributed to what may be considered “short-term” evolution. Papers relevant to putative Coronavirus evolution in both recent and distant time-scales are presented in this volume.


Infectious Bronchitis Virus Mouse Hepatitis Virus Murine Hepatitis Virus Murine Hepatitis Virus Strain Porcine Transmissible Gastroenteritis Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Keck, J.G. et al. ,1988, In vivo RNA-RNA recombination of Coronavirus in mouse brain, J. Virol.. 62: 1810.PubMedGoogle Scholar
  2. 2.
    Kuster, J.G. et al. ,1989, Phylogeny of antigenic variants of avian Coronavirus IBV, Virology, 169:, 217.CrossRefGoogle Scholar
  3. 3.
    Lai, M.M.C. et al. ,Recombination between nonsegmented RNA genomes of murine coronaviruses, J. Virol., 56: 449.Google Scholar
  4. 4.
    Luytjes, W. et al. ,Sequence of mouse hepatitis virus A59 mRNA 2: indications for RNA recombination between coronaviruses and influenza C virus, Virology, 166: 415.Google Scholar
  5. 5.
    Makino, S. et al. ,High frequency RNA recombination of murine coronaviruses, J. Virol., 57: 729.Google Scholar
  6. 6.
    Pensaert, M. et al. ,Isolation of a porcine respiratory, non-enteric Coronavirus related totransmisible gastroenteritis, Vet. Quart., 8: 257.Google Scholar
  7. 7.
    Taguchi, F. et al. ,Characterisation of variant virus selected in rat brains after infection by Coronavirus mouse hepatitis virus JHM, J. Virol., 54: 429.Google Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • D. Cavanagh
    • 1
    • 2
  • T. D. K. Brown
    • 1
    • 2
  1. 1.Houghton LaboratoryAFRC Institute for Animal HealthHuntingdon CambridgeshireUK
  2. 2.Department of PathologyUniversity of CambridgeCambridgeUK

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