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The Haemagglutinin of Bovine Coronavirus Exhibits Significant Similarity to the Haemagglutinin of Type C Influenza Virus

  • Michael D. Parker
  • Graham J. Cox
  • Dongwan Yoo
  • David R. Fitzpatrick
  • Lorne A. Babiuk
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 276)

Abstract

Coronaviruses are large enveloped RNA viruses containing a single-stranded genome complexed with a phosphorylated nucleocapsid protein which is surrounded by an envelope derived from intracellular membranes. The envelope contains two or three species of glycoproteins. The largest, E2 or S, is cleaved to S1 and S2 subunits and forms the large club-shaped peplomers on the surface of the virion which gives the virus its characteristic appearance. The El glycoprotein is believed to be responsible for determining the intracellular site of viral morphogenesis. A smaller group of coronaviruses contain a third membrane glycoprotein (Hogue and Brian, 1986, King et al., 1985, Pocock and Garwes, 1977), E3 or H, which, in the case of bovine Coronavirus , exhibits haemagglutinating and acetylesterase activities.

Keywords

Influenza Virus Haemagglutination Inhibit Murine Hepatitis Virus Bovine Coronavirus National Biomedical Research Foundation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Michael D. Parker
    • 1
  • Graham J. Cox
    • 1
  • Dongwan Yoo
    • 1
  • David R. Fitzpatrick
    • 1
  • Lorne A. Babiuk
    • 1
  1. 1.Veterinary Infectious Disease OrganizationUniversity of SaskatchewanSaskatoonCanada

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