Background Paper Coronavirus M and HE: Two Peculiar Glycoproteins

  • Peter J. M. Rottier
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 276)


Enveloped viruses carry in their membranes one or more surface glycoproteins. In coronaviruses three such proteins have been identified: a small integral membrane protein (M), a large glycoprotein constituting the characteristic viral spikes (S), and an intermediate-sized glycoprotein (HE). This paper will summarize published knowledge on the properties and function of the small and the intermediate-sized membrane proteins. They will be referred to as M and HE, respectively.


Sialic Acid Nucleocapsid Protein Haemagglutinating Activity Membrane Anchor Domain Acetylneuraminic Acid 


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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Peter J. M. Rottier
    • 1
  1. 1.Institute of Infectious Diseases and Immunology Department of Virology Veterinary FacultyState University of UtrechtThe Netherlands

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